Like maybe the main character is obsessed with some hobby and we see this girl who looks sweet and innocent and then she mercilessly mocks his hobby. Maybe even breaking one of his prized possessions. But then as she sees the main character have a mental breakdown, she starts to regret her behavior and does whatever she can to make up for it.
Then maybe you can do something where the girl is a weeb and she looks up to characters like Marin from My Dress-up Darling and she spends the entirety of the series living up to her expectations. To be a best girl, as she fights her impulsive, violent behavior.