G4 was a hodgepodge of canon-except-not-but-kindasorta-are of intermedia continuity.
G5 continues to surprise in that it all seems to be one singular continuity so far, with the exception of the game.
Like the game is building up to Maretime Bay Day, so it’s set before MYM right? And Sprout is there, so it’s probably before TYT too? Except there’s little things like Hitch being able to talk to animals, something that happens at the end of MYM. Or WINGS being not only already established but an actual official program instead of something the Mane 5 slapped together.
Nothing big enough to make it irrefutably incompatible, sure, but enough to make it feel like a separate thing.