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Background Pony #F287
Judging from how you were showed in EQG, the average pony size is only about waist high to an average human(a few exclusions of course since Tia and Luna are clearly taller). Average that height out to the size of their male genitalia and you can roughly estimate that the average human dong is bigger than their stallions. Good enough, Flutters?
Stotter
Wallet After Summer Sale -

@justanotherponi  
Depends on whether diseases can jump species of different worlds. Is their “Earth” enough like ours in terms of genetic evolution not to be considered too alien for a zoonosis? Biology and even physics don’t work the same there, the hippogriff alone being a perfect example.
toxicitzi
BUY SOME APPLES! - Derpi Supporter
My Little Pony - 1992 Edition
Sapphire -
Happy Derpy! - For Patreon supporters

@justanotherponi  
Maybe. Then again, barring contact from other lifeforms forever for this reason is counter to our existence as a species, as we go with the risks to get further.
 
At the same time, this is all a very silly conversation.
justanotherponi
Wallet After Summer Sale -

The Lost Primarch
@Stotter
 
Screw that. Wanna know what I’m more worried about?
 
Diseases.
 
More importantly, Equestria diseases coming over to our world and mutating/spreading like wildfire and vice-versa.
 
While I imagine we are going to share a few already, who knows the differences between them and what new horrors will be unleashed on the medical communities of both worlds just by our worlds interacting.
Stotter
Wallet After Summer Sale -

@Creepa-Bot Inc.  
I’d be terrified for them. Just off the top of my head: Would it be called trafficking or smuggling when it comes to sapient animals? Even at the individual level, there’s approximately a 2% chance of a filly fiddler.
Creepa-Bot Inc.
Condensed Milk - State-Approved Compensation
Friendship, Art, and Magic (2018) - Celebrated Derpibooru's six year anniversary with friends.
Artist -

Well, see, I used to want to go to Equestria……..  
But then I read some fics.  
  • sharp inhale *  
    YYYYYEEEEEAAAAAHHHHHH…….  
    Now the thought of our two worlds ever making contact terrifies me.  
    full
Stotter
Wallet After Summer Sale -

A depressing point is made and bolstered with the earlier one from the same video:  
Going to Equestria doesn’t cure autism.
 
On a desperately needed bright side, where better to get therapy for socialization issues or “friendship problems”?
Brass Melody
Solar Supporter - Fought against the New Lunar Republic rebellion on the side of the Solar Deity (April Fools 2023).
My Little Pony - 1992 Edition
Wallet After Summer Sale -

Gas Loving Baritone Butt
@KingKek42  
Just saying. If they’re willing to put up with having a former cult leader that almost turned Equestria into a wasteland through time meddling, a narcissist magician that enslaved Ponyville, a manchild god of reality who set up no less than three different methods of terraforming the nation into his own playground of annoyance and insanity, and even a forest that’s well known for churning out deadly diseases and even deadlier predators sitting right next to a prestigious town like Ponyville, let alone the home of the nation’s greatest defenders, as acceptable citizens/landmass,
 
then having a sudden influx of bipedal mammals that all evangelize the world these characters inhabit wouldn’t be the worst thing in the world for them.