this is the most accurate thing I have ever seen

@matt4zy
>>112326

@redweasel
They should’ve put the stem through the tail-hole instead. 🥴 Also, I’d hit it. 😉

>imminent vomiting
you underestimate her power

Darn it, Flutters! You’re too cute when using something wrong.

HOW MANY WEEDS DID YOU INJECT!?

@redweasel  
i want this tbh

@moozua  

 
Aw! I was really admiring the cute irony.

@redweasel
 
Reminds me of the baby doll bong from F is for Family

@redweasel  
That’s actually a nice piece. The bowl itself is made of nickle, and the acrylic mouth bit is a nice artistic touch.

@redweasel  
A bong shaped like that is a real rarity.

@moozua
 
to be fair, it is possible that the bowl is built into the pipe, and doesn’t just slip out when you upturn it.
 
I mean someone made this:  

 
so bong designs can get hecka creative

@Mercury_Zero  
If you look at the bong in the first panel and the last, they’re the same picture just flipped and edited a bit. I didn’t really think about it when flipping it. An hour after posting I realized too that water would pour out of a piece as well. Can’t really fix something you posted tho and already got hundreds of notes/retweets on

See how the original source has the bowl facing up? That’s because if you face it downward, like in this comic, it will fall right out.
 
Heh. What does that say about this artist’s experience with bongs? So meta, haha!

Geez the edit window sucks.
 
@redweasel
 
Also yes, paracetamol (Acetaminiphen) is unreasonably dangerous for its intended purpose, and it does make market price of coadministered substance go down, and it is a force of the market.

https://en.wikipedia.org/wiki/Recreational_use_of_dextromethorphan#cite_note-2
 
https://www.drugs.com/mtm/acetaminophen-and-dextromethorphan.html
 
Acetaminiphen is the real culprit. It’s more clear when it’s coasministered with codeine. Why would an effective painkiller be mixed with one that is way less effective and more toxic? There is no synergetic effect of the two, besides hepatitis.

@redweasel  
It’s more that policies go after stand alone preparations.
 
DXM is often combined with acetaminophen (paracetamol, APAP) to relieve pain and to prevent recreational use;[2]  
DXM is a more powerful painkiller than acetaminophen, so the first reason is obviously damage control. Recreational use also refers to the window in which it can be used to achieve pain killing effects comparable to morphine, it just turns out that functional painkillers with high theraputic windows are a target of abuse.
 
Mixing drugs to prevent ‘abuse’ (and consequentially informed use outside the market niche) is seen in antihistamines, cough medicine, codiene containing products, analgestics, hypnotics, laxatives and decongestants.

@Ninji
 
so, they add deadly paracetamol, and that makes the price go down. well uh… market… forces at work, I guess?
 

Also yes, global depressants cause debilitating metabolic cascades when suddenly removed.
 
NMDA antagonist don’t cause delirium tremens, painful sensitivity to stimulus or shaking nausea. NMDA is one of the three unique classes of ionotropic glutamate receptors and for some reason blocking NMDA globally causes way fewer imbalances than an opiod, and the withdraw is a clean comfortable stimulation from my experience, the kind that makes me clean the house and get back to work.

@redweasel  
Nah the bromide is just dirty cheap drug manufacturing. The deliberate adding of ineffective drugs with tiny therapeutic windows is the anti abuse. I figured this out in the pursuit of clean extractions of various substances. The only time a company will outright claim ‘anti-abuse’ is when they’re sure it’s not going to backfire on them, but if you look into the history of codeine or DXM you’ll find many rather toxic preparations being pefered to one active chemical, in order to ‘combat abuse’.
 
Well you can get DXM by itself, but it’s 10-20 times more expensive for much less product. I’ve found 200mg bottles going for 20usd, but when it has the 64mg of CPM co-administered suddenly you can get an entire gram for 5usd (two dollar store HBP Cough and Cold)

@Ninji
 
okay yeah, I thought you knew somewhere where amphetamine was legal and they banned it to replace it with phenylephedrine. now that would be a travesty.
 

in a nutshell, there’s three pain pills: hydrocodone, codeine, and rarely dihydrocodeine. once ingested, codeine metabolizes into morphine, hydrocodone into hydromorphone which is even more powerful than morphine, and dihydromorphine which… I’m not sure of its effect relative to morphine. doctors don’t inform their patients of this, acting like codeine isn’t as addictive as morphine. that’s the primary reason there’s such a terrible heroin problem in the usa.
 

yeah I… can kind of see that. erowid says that it’s not enough bromine to cause bromism, but they’re focusing on doing it occasionally for fun, rather than over a longer period of time for pain management. bromine accumulates in the body, if you take it more than once every 14 days or so.
 
and there’s absolutely no reason they couldn’t use hcl. you can even do the acid-base extraction to convert it in your backyard. but I can’t find anyone (besides you) claiming that the reason hbr was used instead of hcl was to curb the abuse of the drug. wouldn’t pharmaceuticals market hbr as “anti-abuse” if they wanted an excuse to poison poor people?

@redweasel  
I never had a reason to look into codeine. If I get something like a dental abscess I cold water filter DXM and go to the ER to get free antibiotics.
 
DXM is also an example of a drug that gets put on hydrogen bromide with hcl will work just fine (hcl base will increase bioavailability too). It’s arguably one of the most valuable drugs on the shelf, so they go after the abuse aspect, which is often just kids or homeless people with no access to proper health care.
 
Yeah DXM is where racemorphan meets ketamine. NMDA antagonist and opiode receptor antagonist stop pain in its tracks. However NMDA antagonist not only have less physical repercussions, but the withdraw is also amazing euphoria (which is why people don’t usually habit DXM or PCP) and NMDA is a bunch bigger class of receptors, where phychogenic pain and even the ability to form addictions is also interrupted.
 
Lots of times substances with low therapeutic indexes are added as ‘anti-abuse’ , but there is all sorts of shit to abuse, and it’s usually drugs with high utility to poor people that get targeted.
 
Yes phenylephedrine replaced pseudoephedrine, little more than a simple reduction can turn pseudoephedrine into racemic amphetamine (half the molocules will go dextro, half will go levo)

@Ninji
 
I never understood how they could make regular amphetamine salts illegal. they aren’t even particularly pleasant to take, much less addictive. yet even doctors aren’t allowed to prescribe them, without checking every month to ensure you didn’t go natty bonkers for some reason. it’s just so obviously a ludicrous guilt trip cash grab.
 
but I think phenylephedrine replaced pseudoephedrine, not plain (dextro)amphetamine which was just flat out banned. when pseudoephedrine vanished, I remember the news said it was to make it harder to cook meth, thus securing the meth market for mexican drug lords. I agree it is stupid they tried to replace it with phenylephedrine, which isn’t even a decongestant and only has unpleasant side effects.
 
the “totes-not-opium” painkiller of choice these days I thought was codeine, not morphine. all opium based drugs metabolize into the same thing as opium pretty quickly, whether it’s morphine, heroin, or codeine, so I guess you could call them the same thing. I never heard of dxm actually. wikipedia says it’s in the same class of drugs as ketamine?
 
and… yes I already know I can search for bromide. what I wanted you to say was that chronic ingestion of brominated salts (bromides) leads to bromism: a malady characterized by psychosis, hallucinations, nasty skin rash, constipation, and rarely leads to a coma. when it would be cheaper and safer to just use table salt instead.
 
but I don’t know of any stores that use bromides anymore, not even dollar stores. I thought the only place it was used anymore is outside the usa, as a potential treatment specifically for epilepsy. are the pill makers in the usa just ignoring the fda?

@redweasel  
DXM is a powerful painkiller at high doses, massively undercutting redbook morphine, so a veterinarian antihistamine is added to it, to make it harder to use for pain/psychological reasons.
 
Bromide was withdrawn from mainstream use for chronic toxicity. Now it’s relegated to use in cheap dollar store drugs that would readily accept a nontoxic hydrogen chloride base.
 
Phynleephedrine doesn’t even work, it failed all trials, but is sold anyway to combat poor peoples access to dextroamphetamine, a proven effective phychostimulant that undercuts the sale of aftermarket seratonin drugs, which also fail most trials.
 
EDIT: I don’t know your familiarity with these substances, but you can google a substance like Bromide. You’ll also find undesirable alternatives showing up for questionable reasons, such as chlorphenamine.

@Ninji
 

 
citation needed.
 
no seriously, you can’t just say that and leave us hanging. what medicine, who approved that, what co-administered drug, and what’s poisonous about a bromide base?
 
the worst I heard of was the patent trolling by the claritin corporation, selling an antihistamine mixed with an allergen, then once that patent expired, selling the actual drug, claiming “not-mixing-with-an-allergen” allows them to patent it again, thus sabatoging all competing generic brands of cetirizine.